What’s In your Juvederm? You May Be Pleasantly Surprised!

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What is Juvederm?
Juvederm1Juvederm contains a glycosaminoglycan normally distributed widely throughout epithelial connective, and neural tissues in humans. But you may know this glycosaminoglycan better as hyaluronic acid. Until the late 1970’s, hyaluronic acid was described as a “goo” molecule, a ubiquitous carbohydrate, likely in any skincare section of a multitude of departments stores.

What is Hyaluronic Acid?

Why all the fuss over this ubiquitous polymer? Hyaluronanic acid is also a major component of skin, where it is involved in tissue repair. When skin is exposed to excessive UVB rays, it becomes inflamed (sunburn) and the cells in the dermis stop producing as much hyaluronan, and increase the rate of its degradation. Hyaluronan degradation products then accumulate in the skin after UVexposure.

Hyaluronic acid potently binds to water and, when injected into the skin, volumizes, softens, and hydrates the skin. In addition to these benefits, it plays a role in cell growth, membrane receptor function, and adhesion.

Hyaluronic acid stabilizes intercellular structures and produces the viscoelastic network for collagen and elastin fibers to bind together. As seen with photoaging, these connections fail, thus resulting in disorganized clumps of collagen and elastin. These benefits make hyaluronic acid an excellent dermal filling agent. In February 2003, the FDA approved Restylane, a cross-linked, nonanimal source hyaluronic acid.

So where does Hyaluronic Acid in Juvederm come from?

The hyaluronic acid in dermal fillers is actually derived from bacterial fermentation from specific strains of streptococci (streptococcus equii). However, there are no harmful bacteria present in the filler product itself.

Surprising isn’t it? But according to sciencedaily.com: 26% of approved drugs are nature-derived. Today, about half of the drugs on the market were discovered by screening collections of small molecules made by bacteria, fungi, snails, leeches and other such species. Whether you have a mild headache or you are running a fever, there is a high chance that the drug that is used to treat you comes from nature. Even common drugs like Aspirin are nature-derived. For more information on nature-derived medicine visit the link: https://www.sciencedaily.com/releases/2011/08/110831081551.htm  

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